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Tiwari, K. N. and Monserrat, J. P. and Hequet, A. and Ganem-Elbaz, C. and Cresteil, T. and Jaouen, G. and Vessieres, A. and Hillard, E. A. and Jolivalt, C.
In vitro inhibitory properties of ferrocene-substituted chalcones and aurones on bacterial and human cell cultures
Dalton Trans (2012)
41, 6451-7
10.1039/c2dt12180h
Tora, A. S. and Rovira, X. and Dione, I. and Bertrand, H. O. and Brabet, I. and De Koninck, Y. and Doyon, N. and Pin, J. P. and Acher, F. and Goudet, C.
Allosteric modulation of metabotropic glutamate receptors by chloride ions
FASEB J (2015)
29, 4174-88
10.1096/fj.14-269746
Traore, T. and Delacour, L. and Garcia-Argote, S. and Berthault, P. and Cintrat, J. C. and Rousseau, B.
Scalable synthesis of cryptophane-1.1.1 and its functionalization
Org Lett (2010)
12, 960-2
10.1021/ol902952h
Treguier, B. and Lawson, M. and Bernadat, G. and Bignon, J. and Dubois, J. and Brion, J. D. and Alami, M. and Hamze, A.
Synthesis of a 3-(alpha-styryl)benzo[b]-thiophene library via bromocyclization of alkynes and palladium-catalyzed to sylhydrazones cross-couplings: evaluation as antitubulin agents
ACS Comb Sci (2014)
16, 702-10
10.1021/co500115b
Trepiccione, F. and Soukaseum, C. and Baudrie, V. and Kumai, Y. and Teulon, J. and Villoutreix, B. and Corniere, N. and Wangemann, P. and Griffith, A. J. and Byung Choi, Y. and Hadchouel, J. and Chambrey, R. and Eladari, D.
Acute genetic ablation of pendrin lowers blood pressure in mice
Nephrol Dial Transplant (2017)
32, 1137-1145
10.1093/ndt/gfw393
Trofimov, V. and Costa-Gouveia, J. and Hoffmann, E. and Brodin, P.
Host-pathogen systems for early drug discovery against tuberculosis
Curr Opin Microbiol (2017)
39, 143-151
10.1016/j.mib.2017.11.017
Trovaslet-Leroy, M. and Jolivalt, C. and Froment, M. T. and Brasme, B. and Lefebvre, B. and Daveloose, D. and Nachon, F. and Masson, P.
Application of laccase-mediator system (LMS) for the degradation of organophosphorus compounds
Chem Biol Interact (2010)
187, 393-6
10.1016/j.cbi.2010.02.001
Tudor, D. and Yu, H. and Maupetit, J. and Drillet, A. S. and Bouceba, T. and Schwartz-Cornil, I. and Lopalco, L. and Tuffery, P. and Bomsel, M.
Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody
Proc Natl Acad Sci U S A (2012)
109, 12680-5
10.1073/pnas.1200024109
Tuffery, P.
Accessing external innovation in drug discovery and development
Expert Opin Drug Discov (2015)
10, 579-89
10.1517/17460441.2015.1040759
Tuffery, P. and Derreumaux, P.
Flexibility and binding affinity in protein-ligand, protein-protein and multi-component protein interactions: limitations of current computational approaches
J R Soc Interface (2012)
9, 20-33
10.1098/rsif.2011.0584
Tufo, G. and Jones, A. W. and Wang, Z. and Hamelin, J. and Tajeddine, N. and Esposti, D. D. and Martel, C. and Boursier, C. and Gallerne, C. and Migdal, C. and Lemaire, C. and Szabadkai, G. and Lemoine, A. and Kroemer, G. and Brenner, C.
The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma
Cell Death Differ (2014)
21, 685-95
10.1038/cdd.2013.193
Turapov, O. and Waddell, S. J. and Burke, B. and Glenn, S. and Sarybaeva, A. A. and Tudo, G. and Labesse, G. and Young, D. I. and Young, M. and Andrew, P. W. and Butcher, P. D. and Cohen-Gonsaud, M. and Mukamolova, G. V.
Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria
J Biol Chem (2014)
289, 25241-9
10.1074/jbc.M114.577338
Turpaev, K. and Ermolenko, M. and Cresteil, T. and Drapier, J. C.
Benzylidenemalononitrile compounds as activators of cell resistance to oxidative stress and modulators of multiple signaling pathways. A structure-activity relationship study
Biochem Pharmacol (2011)
82, 535-47
10.1016/j.bcp.2011.05.028
Ufarte, L. and Bozonnet, S. and Laville, E. and Cecchini, D. A. and Pizzut-Serin, S. and Jacquiod, S. and Demaneche, S. and Simonet, P. and Franqueville, L. and Veronese, G. P.
Functional Metagenomics: Construction and High-Throughput Screening of Fosmid Libraries for Discovery of Novel Carbohydrate-Active Enzymes
Methods Mol Biol (2016)
1399, 257-71
10.1007/978-1-4939-3369-3_15
Ulferts, R. and de Boer, S. M. and van der Linden, L. and Bauer, L. and Lyoo, H. R. and Mate, M. J. and Lichiere, J. and Canard, B. and Lelieveld, D. and Omta, W. and Egan, D. and Coutard, B. and van Kuppeveld, F. J.
Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C
Antimicrob Agents Chemother (2016)
60, 2627-38
10.1128/AAC.02182-15
Prudent, R. and Vassal-Stermann, E. and Nguyen, C. H. and Mollaret, M. and Viallet, J. and Desroches-Castan, A. and Martinez, A. and Barette, C. and Pillet, C. and Valdameri, G. and Soleilhac, E. and Di Pietro, A. and Feige, J. J. and Billaud, M. and Florent, J. C. and Lafanechere, L.
Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities
Br J Pharmacol (2013)
168, 673-85
10.1111/j.1476-5381.2012.02230.x
Prudent, R. and Vassal-Stermann, E. and Nguyen, C. H. and Pillet, C. and Martinez, A. and Prunier, C. and Barette, C. and Soleilhac, E. and Filhol, O. and Beghin, A. and Valdameri, G. and Honore, S. and Aci-Seche, S. and Grierson, D. and Antonipillai, J. and Li, R. and Di Pietro, A. and Dumontet, C. and Braguer, D. and Florent, J. C. and Knapp, S. and Bernard, O. and Lafanechere, L.
Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth
Cancer Res (2012)
72, 4429-39
10.1158/0008-5472.CAN-11-3342
Prunier, C. and Josserand, V. and Vollaire, J. and Beerling, E. and Petropoulos, C. and Destaing, O. and Montemagno, C. and Hurbin, A. and Prudent, R. and de Koning, L. and Kapur, R. and Cohen, P. A. and Albiges-Rizo, C. and Coll, J. L. and van Rheenen, J. and Billaud, M. and Lafanechere, L.
LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers
Cancer Res (2016)
76, 3541-52
10.1158/0008-5472.CAN-15-1864
Prunier, C. and Kapur, R. and Lafanechere, L.
Targeting LIM kinases in taxane resistant tumors
Oncotarget (2016)
7, 50816-50817
10.18632/oncotarget.10816
Prunier, C. and Prudent, R. and Kapur, R. and Sadoul, K. and Lafanechere, L.
LIM kinases: cofilin and beyond
Oncotarget (2017)
8, 41749-41763
10.18632/oncotarget.16978
Pulido, M. and Roubaud, G. and Cazeau, A. L. and Mahammedi, H. and Vedrine, L. and Joly, F. and Mourey, L. and Pfister, C. and Goberna, A. and Lortal, B. and Bellera, C. and Pourquier, P. and Houede, N.
Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer
BMC Cancer (2018)
18, 194
10.1186/s12885-018-4059-5
Putey, A. and Fournet, G. and Lozach, O. and Perrin, L. and Meijer, L. and Joseph, B.
Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors
Eur J Med Chem (2014)
83, 617-29
10.1016/j.ejmech.2014.06.063
Quemener, A. and Maillasson, M. and Arzel, L. and Sicard, B. and Vomiandry, R. and Mortier, E. and Dubreuil, D. and Jacques, Y. and Lebreton, J. and Mathe-Allainmat, M.
Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization
J Med Chem (2017)
60, 6249-6272
10.1021/acs.jmedchem.7b00485
Queval, C. J. and Song, O. R. and Carralot, J. P. and Saliou, J. M. and Bongiovanni, A. and Deloison, G. and Deboosere, N. and Jouny, S. and Iantomasi, R. and Delorme, V. and Debrie, A. S. and Park, S. J. and Gouveia, J. C. and Tomavo, S. and Brosch, R. and Yoshimura, A. and Yeramian, E. and Brodin, P.
Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
Cell Rep (2017)
20, 3188-3198
10.1016/j.celrep.2017.08.101
Queval, C. J. and Song, O. R. and Deboosere, N. and Delorme, V. and Debrie, A. S. and Iantomasi, R. and Veyron-Churlet, R. and Jouny, S. and Redhage, K. and Deloison, G. and Baulard, A. and Chamaillard, M. and Locht, C. and Brodin, P.
STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection
Sci Rep (2016)
6, 29297
10.1038/srep29297
Quiedeville, A. and Boulouard, M. and Hamidouche, K. and Da Silva Costa-Aze, V. and Nee, G. and Rochais, C. and Dallemagne, P. and Fabis, F. and Freret, T. and Bouet, V.
Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances
Behav Brain Res (2015)
293, 10-7
10.1016/j.bbr.2015.07.020
Quillet, R. and Ayachi, S. and Bihel, F. and Elhabazi, K. and Ilien, B. and Simonin, F.
RF-amide neuropeptides and their receptors in Mammals: Pharmacological properties, drug development and main physiological functions
Pharmacol Ther (2016)
160, 84-132
10.1016/j.pharmthera.2016.02.005
Quillet, R. and Simonin, F.
[The neuropeptide FF: a signal for M1 to M2 type switching in macrophages from the adipose tissue]
Med Sci (Paris) (2018)
34, 27-29
10.1051/medsci/20183401008
Quintard, A. and Cheshmedzhieva, D. and Sanchez Duque Mdel, M. and Gaudel-Siri, A. and Naubron, J. V. and Genisson, Y. and Plaquevent, J. C. and Bugaut, X. and Rodriguez, J. and Constantieux, T.
Origin of the enantioselectivity in organocatalytic Michael additions of beta-ketoamides to alpha,beta-unsaturated carbonyls: a combined experimental, spectroscopic and theoretical study
Chemistry (2015)
21, 778-90
10.1002/chem.201404481
Rabhi, C. and Arcile, G. and Cariel, L. and Lenoir, C. and Bignon, J. and Wdzieczak-Bakala, J. and Ouazzani, J.
Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants
J Med Food (2015)
18, 1065-72
10.1089/jmf.2014.0128
Raffy, Q. and Buisson, D. A. and Cintrat, J. C. and Rousseau, B. and Pin, S. and Renault, J. P.
Carbon-centered radicals can transfer hydrogen atoms between amino acid side chains
Angew Chem Int Ed Engl (2012)
51, 2960-3
10.1002/anie.201108856
Raj, S. and Krishnan, K. and Askew, D. S. and Helynck, O. and Suzanne, P. and Lesnard, A. and Rault, S. and Zeidler, U. and d'Enfert, C. and Latge, J. P. and Munier-Lehmann, H. and Saveanu, C.
The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components
Antimicrob Agents Chemother (2015)
60, 1438-49
10.1128/AAC.02239-15
Rajapakse, C. S. and Lisai, M. and Deregnaucourt, C. and Sinou, V. and Latour, C. and Roy, D. and Schrevel, J. and Sanchez-Delgado, R. A.
Synthesis of New 4-Aminoquinolines and Evaluation of Their In Vitro Activity against Chloroquine-Sensitive and Chloroquine-Resistant Plasmodium falciparum
PLoS One (2015)
10, e0140878
10.1371/journal.pone.0140878
Ramanjooloo, A. and Cresteil, T. and Lebrasse, C. and Beedessee, G. and Oogarah, P. and van Soest, R. W. and Marie, D. E.
alpha-Glucosidase inhibitory activity of marine sponges collected in Mauritius waters
Nat Prod Res (2015)
29, 383-7
10.1080/14786419.2014.945173
Raux, B. and Voitovich, Y. and Derviaux, C. and Lugari, A. and Rebuffet, E. and Milhas, S. and Priet, S. and Roux, T. and Trinquet, E. and Guillemot, J. C. and Knapp, S. and Brunel, J. M. and Fedorov, A. Y. and Collette, Y. and Roche, P. and Betzi, S. and Combes, S. and Morelli, X.
Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins
J Med Chem (2016)
59, 1634-41
10.1021/acs.jmedchem.5b01708
Ray, A. M. and Schaffner, F. and Janouskova, H. and Noulet, F. and Rognan, D. and Lelong-Rebel, I. and Choulier, L. and Blandin, A. F. and Lehmann, M. and Martin, S. and Kapp, T. and Neubauer, S. and Rechenmacher, F. and Kessler, H. and Dontenwill, M.
Single cell tracking assay reveals an opposite effect of selective small non-peptidic alpha5beta1 or alphavbeta3/beta5 integrin antagonists in U87MG glioma cells
Biochim Biophys Acta (2014)
1840, 2978-87
10.1016/j.bbagen.2014.04.024
Rederstorff, M. and Castets, P. and Arbogast, S. and Laine, J. and Vassilopoulos, S. and Beuvin, M. and Dubourg, O. and Vignaud, A. and Ferry, A. and Krol, A. and Allamand, V. and Guicheney, P. and Ferreiro, A. and Lescure, A.
Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy
PLoS One (2011)
6, e23094
10.1371/journal.pone.0023094
Regenass, P. and Bosc, D. and Riche, S. and Gizzi, P. and Hibert, M. and Karmazin, L. and Ganesan, A. and Bonnet, D.
Comparative Study of the Synthesis and Structural and Physicochemical Properties of Diketopiperazines vs Aza-diketopiperazines
J Org Chem (2017)
82, 3239-3244
10.1021/acs.joc.6b02895
Regenass, P. and Margathe, J. F. and Mann, A. and Suffert, J. and Hibert, M. and Girard, N. and Bonnet, D.
Diastereoselective synthesis of novel aza-diketopiperazines via a domino cyclohydrocarbonylation/addition process
Chem Commun (Camb) (2014)
50, 9657-60
10.1039/c4cc03660c
Regenass, P. and Riche, S. and Peron, F. and Rognan, D. and Hibert, M. and Girard, N. and Bonnet, D.
A step-economical multicomponent synthesis of 3D-shaped aza-diketopiperazines and their drug-like chemical space analysis
Org Biomol Chem (2016)
14, 8859-8863
10.1039/c6ob01434h
Renard, B. L. and Boucherle, B. and Maurin, B. and Molina, M. C. and Norez, C. and Becq, F. and Decout, J. L.
An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors
Eur J Med Chem (2011)
46, 1935-41
10.1016/j.ejmech.2011.02.037
Renaud, V. and Godefroy, E. and Larrieu, P. and Fleury, F. and Jotereau, F. and Guilloux, Y.
Folding of matrix metalloproteinase-2 prevents endogenous generation of MHC class-I restricted epitope
PLoS One (2010)
5, e11894
10.1371/journal.pone.0011894
Renko, D. and Provot, O. and Rasolofonjatovo, E. and Bignon, J. and Rodrigo, J. and Dubois, J. and Brion, J. D. and Hamze, A. and Alami, M.
Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents
Eur J Med Chem (2015)
90, 834-44
10.1016/j.ejmech.2014.12.024
Rerole, A. L. and Gobbo, J. and De Thonel, A. and Schmitt, E. and Pais de Barros, J. P. and Hammann, A. and Lanneau, D. and Fourmaux, E. and Demidov, O. N. and Micheau, O. and Lagrost, L. and Colas, P. and Kroemer, G. and Garrido, C.
Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy
Cancer Res (2011)
71, 484-95
10.1158/0008-5472.CAN-10-1443
Rey, J. and Deschavanne, P. and Tuffery, P.
BactPepDB: a database of predicted peptides from a exhaustive survey of complete prokaryote genomes
Database (Oxford) (2014)
2014,
10.1093/database/bau106
Rey-Rodriguez, R. and Retailleau, P. and Bonnet, P. and Gillaizeau, I.
Iron-catalyzed trifluoromethylation of enamide
Chemistry (2015)
21, 3572-5
10.1002/chem.201406333
Reynes, C. and Host, H. and Camproux, A. C. and Laconde, G. and Leroux, F. and Mazars, A. and Deprez, B. and Fahraeus, R. and Villoutreix, B. O. and Sperandio, O.
Designing focused chemical libraries enriched in protein-protein interaction inhibitors using machine-learning methods
PLoS Comput Biol (2010)
6, e1000695
10.1371/journal.pcbi.1000695
Ribeiro, N. and Thuaud, F. and Bernard, Y. and Gaiddon, C. and Cresteil, T. and Hild, A. and Hirsch, E. C. and Michel, P. P. and Nebigil, C. G. and Desaubry, L.
Flavaglines as potent anticancer and cytoprotective agents
J Med Chem (2012)
55, 10064-73
10.1021/jm301201z
Ripoll, M. and Neuberg, P. and Kichler, A. and Tounsi, N. and Wagner, A. and Remy, J. S.
pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery
ACS Appl Mater Interfaces (2016)
8, 30665-30670
10.1021/acsami.6b09365
Riva, L. and Song, O. R. and Prentoe, J. and Helle, F. and L'Homme, L. and Gattolliat, C. H. and Vandeputte, A. and Feneant, L. and Belouzard, S. and Baumert, T. F. and Asselah, T. and Bukh, J. and Brodin, P. and Cocquerel, L. and Rouille, Y. and Dubuisson, J.
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry
J Virol (2018)
92,
10.1128/JVI.01982-17
Rivat, C. and Sar, C. and Mechaly, I. and Leyris, J. P. and Diouloufet, L. and Sonrier, C. and Philipson, Y. and Lucas, O. and Mallie, S. and Jouvenel, A. and Tassou, A. and Haton, H. and Venteo, S. and Pin, J. P. and Trinquet, E. and Charrier-Savournin, F. and Mezghrani, A. and Joly, W. and Mion, J. and Schmitt, M. and Pattyn, A. and Marmigere, F. and Sokoloff, P. and Carroll, P. and Rognan, D. and Valmier, J.
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice
Nat Commun (2018)
9, 1042
10.1038/s41467-018-03496-2
Rives, A. and Baudoin-Dehoux, C. and Saffon, N. and Andrieu-Abadie, N. and Genisson, Y.
Asymmetric synthesis and cytotoxic activity of isomeric phytosphingosine derivatives
Org Biomol Chem (2011)
9, 8163-70
10.1039/c1ob06195j
Rives, A. and Ladeira, S. and Levade, T. and Andrieu-Abadie, N. and Genisson, Y.
Synthesis of cytotoxic aza analogues of jaspine B
J Org Chem (2010)
75, 7920-3
10.1021/jo1014239
Rizza, P. and Pellegrino, M. and Caruso, A. and Iacopetta, D. and Sinicropi, M. S. and Rault, S. and Lancelot, J. C. and El-Kashef, H. and Lesnard, A. and Rochais, C. and Dallemagne, P. and Saturnino, C. and Giordano, F. and Catalano, S. and Ando, S.
3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progression
Eur J Med Chem (2016)
107, 275-87
10.1016/j.ejmech.2015.11.004
Rochais, C. and Cresteil, T. and Perri, V. and Jouanne, M. and Lesnard, A. and Rault, S. and Dallemagne, P.
MR22388, a novel anti-cancer agent with a strong FLT-3 ITD kinase affinity
Cancer Lett (2013)
331, 92-8
10.1016/j.canlet.2012.12.017
Rochais, C. and Lecoutey, C. and Gaven, F. and Giannoni, P. and Hamidouche, K. and Hedou, D. and Dubost, E. and Genest, D. and Yahiaoui, S. and Freret, T. and Bouet, V. and Dauphin, F. and Sopkova de Oliveira Santos, J. and Ballandonne, C. and Corvaisier, S. and Malzert-Freon, A. and Legay, R. and Boulouard, M. and Claeysen, S. and Dallemagne, P.
Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride
J Med Chem (2015)
58, 3172-87
10.1021/acs.jmedchem.5b00115
Rochais, C. and Rault, S. and Dallemagne, P.
Intramolecular cyclisation of beta-aryl-beta-amino acids in the design of novel heterocyclic systems with therapeutic interest: an unfailing source of diversity
Curr Med Chem (2010)
17, 4342-69
Roche, M. and Salim, S. M. and Bignon, J. and Levaique, H. and Brion, J. D. and Alami, M. and Hamze, A.
Palladium-Catalyzed One-Pot Reaction of Hydrazones, Dihaloarenes, and Organoboron Reagents: Synthesis and Cytotoxic Activity of 1,1-Diarylethylene Derivatives
J Org Chem (2015)
80, 6715-27
10.1021/acs.joc.5b00880
Rode, B. and Dirami, T. and Bakouh, N. and Rizk-Rabin, M. and Norez, C. and Lhuillier, P. and Lores, P. and Jollivet, M. and Melin, P. and Zvetkova, I. and Bienvenu, T. and Becq, F. and Planelles, G. and Edelman, A. and Gacon, G. and Toure, A.
The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation
Hum Mol Genet (2012)
21, 1287-98
10.1093/hmg/ddr558
Roeckel, L. A. and Le Coz, G. M. and Gaveriaux-Ruff, C. and Simonin, F.
Opioid-induced hyperalgesia: Cellular and molecular mechanisms
Neuroscience (2016)
338, 160-182
10.1016/j.neuroscience.2016.06.029
Roeckel, L. A. and Utard, V. and Reiss, D. and Mouheiche, J. and Maurin, H. and Robe, A. and Audouard, E. and Wood, J. N. and Goumon, Y. and Simonin, F. and Gaveriaux-Ruff, C.
Morphine-induced hyperalgesia involves mu opioid receptors and the metabolite morphine-3-glucuronide
Sci Rep (2017)
7, 10406
10.1038/s41598-017-11120-4
Roelants, C. and Giacosa, S. and Pillet, C. and Bussat, R. and Champelovier, P. and Bastien, O. and Guyon, L. and Arnoux, V. and Cochet, C. and Filhol, O.
Combined inhibition of PI3K and Src kinases demonstrates synergistic therapeutic efficacy in clear-cell renal carcinoma
Oncotarget (2018)
9, 30066-30078
10.18632/oncotarget.25700
Rognan, D.
Fragment-based approaches and computer-aided drug discovery
Top Curr Chem (2012)
317, 201-22
10.1007/128_2011_182
Rognan, D.
Towards the Next Generation of Computational Chemogenomics Tools
Mol Inform (2013)
32, 1029-34
10.1002/minf.201300054
Rognan, D.
The impact of in silico screening in the discovery of novel and safer drug candidates
Pharmacol Ther (2017)
175, 47-66
10.1016/j.pharmthera.2017.02.034
Rognan, D. and Bonnet, P.
[Chemical databases and virtual screening]
Med Sci (Paris) (2014)
30, 1152-60
10.1051/medsci/20143012019
Rognan, D. and Varnek, A.
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